Abstract
Methicillin-resistant Staphylococcus aureus (MRSA) has since become a major cause of illness and death in our healthcare setting. Risk factors for HA-MRSA include hospitalization, older age, invasive devices, and residence in long-term care facility, including exposure to antimicrobial agents. HA-MRSA isolates are often resistant to several antimicrobial drug classes in addition to beta-lactams. The CA-MRSA infections usually affects young, healthy persons and associated with sharing towels or athletic equipment, participating in contact sports, living in unsanitary and crowded areas, using illegal intravenous drugs. The number of invasive MRSA infections reported and the number of invasive infections caused by CA-MRSA is on the increase. The increase of CA-MRSA poses a unique public health threat. It is now clear that CA-MRSA no longer causes only SSTIs but now causes an increased proportion of invasive infections in a rural state. This should further inform and direct prospective researches and policies in developing specific tools to meet the needs.