<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article PUBLIC "-//NLM//DTD Journal Publishing DTD v2.0 20040830//EN" "journalpublishing.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" dtd-version="2.0" xml:lang="en" article-type="research-article"><front><journal-meta><journal-id journal-id-type="nlm-ta">Online J Public Health Inform</journal-id><journal-id journal-id-type="publisher-id">ojphi</journal-id><journal-id journal-id-type="index">45</journal-id><journal-title>Online Journal of Public Health Informatics</journal-title><abbrev-journal-title>Online J Public Health Inform</abbrev-journal-title><issn pub-type="epub">1947-2579</issn><publisher><publisher-name>JMIR Publications</publisher-name><publisher-loc>Toronto, Canada</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">v17i1e72909</article-id><article-id pub-id-type="doi">10.2196/72909</article-id><article-categories><subj-group subj-group-type="heading"><subject>Original Paper</subject></subj-group></article-categories><title-group><article-title>Evaluation of a Sentinel Hypertension Surveillance System in Mojo, East Shewa Zone, Oromia, Ethiopia: Concurrently Embedded Mixed Design Study</article-title></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name name-style="western"><surname>Demelash Gashe</surname><given-names>Abiyie</given-names></name><degrees>BSc, MPH</degrees><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib contrib-type="author"><name name-style="western"><surname>Ayale Ferede</surname><given-names>Yeshiwas</given-names></name><degrees>BSc, MPH</degrees><xref ref-type="aff" rid="aff2">2</xref></contrib><contrib contrib-type="author"><name name-style="western"><surname>Zenebe Weldemichael</surname><given-names>Dawit</given-names></name><degrees>BSc, MPH</degrees><xref ref-type="aff" rid="aff3">3</xref></contrib><contrib contrib-type="author"><name name-style="western"><surname>Yesuf Endries</surname><given-names>Aman</given-names></name><degrees>BSc, MPH</degrees><xref ref-type="aff" rid="aff4">4</xref></contrib></contrib-group><aff id="aff1"><institution>Ethiopian Field Epidemiology Training Program, Department of Epidemiology, School of Public Health, St. Paul's Hospital Millennium Medical College</institution><addr-line>Addis Ababa</addr-line><country>Ethiopia</country></aff><aff id="aff2"><institution>Department of Reproductive Health, Teda Health Science College</institution><addr-line>Gondar</addr-line><country>Ethiopia</country></aff><aff id="aff3"><institution>Department of Epidemiology, College of Health Science, Mekelle University</institution><addr-line>Mek'ele</addr-line><country>Ethiopia</country></aff><aff id="aff4"><institution>Department of Epidemiology, School of Public Health, St. Paul's Hospital Millennium Medical College</institution><addr-line>Addis Ababa</addr-line><country>Ethiopia</country></aff><contrib-group><contrib contrib-type="editor"><name name-style="western"><surname>Mensah</surname><given-names>Edward</given-names></name></contrib></contrib-group><contrib-group><contrib contrib-type="reviewer"><name name-style="western"><surname>Adekola</surname><given-names>Adeleke</given-names></name></contrib><contrib contrib-type="reviewer"><name name-style="western"><surname>Udensi</surname><given-names>Chukwuma</given-names></name></contrib></contrib-group><author-notes><corresp>Correspondence to Abiyie Demelash Gashe, BSc, MPH, Ethiopian Field Epidemiology Training Program, Department of Epidemiology, School of Public Health, St. Paul's Hospital Millennium Medical College, Addis Ababa, 1000, Ethiopia, 251945142918; <email>abiyiedemelash@gmail.com</email></corresp></author-notes><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>3</day><month>6</month><year>2025</year></pub-date><volume>17</volume><elocation-id>e72909</elocation-id><history><date date-type="received"><day>20</day><month>02</month><year>2025</year></date><date date-type="rev-recd"><day>24</day><month>03</month><year>2025</year></date><date date-type="accepted"><day>10</day><month>04</month><year>2025</year></date></history><copyright-statement>&#x00A9; Abiyie Demelash Gashe, Yeshiwas Ayale Ferede, Dawit Zenebe Weldemichael, Aman Yesuf Endries. Originally published in the Online Journal of Public Health Informatics (<ext-link ext-link-type="uri" xlink:href="https://ojphi.jmir.org/">https://ojphi.jmir.org/</ext-link>), 3.6.2025. </copyright-statement><copyright-year>2025</copyright-year><license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/"><p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (<ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by/4.0/">https://creativecommons.org/licenses/by/4.0/</ext-link>), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in the Online Journal of Public Health Informatics, is properly cited. The complete bibliographic information, a link to the original publication on <ext-link ext-link-type="uri" xlink:href="https://ojphi.jmir.org/">https://ojphi.jmir.org/</ext-link>, as well as this copyright and license information must be included.</p></license><self-uri xlink:type="simple" xlink:href="https://ojphi.jmir.org/2025/1/e72909"/><abstract><sec><title>Background</title><p>In response to the increasing incidence and prevalence of hypertension, Ethiopia has been piloting hypertension control at the primary health care level in selected sentinel sites. However, no evaluation has been conducted and its success and failures have not been ascertained.</p></sec><sec><title>Objective</title><p>This study aimed to evaluate on whether sentinel hypertension surveillance system in Mojo City were operating efficiently and effectively.</p></sec><sec sec-type="methods"><title>Methods</title><p>A concurrently embedded mixed design (quantitative or qualitative) study was conducted in 2 sentinel health centers in Mojo city, Oromia region of Ethiopia. The usefulness and 9 system attributes were assessed via key informant interviews, observations, and record reviews. The qualitative data were analyzed manually via thematic analysis, whereas quantitative data were analyzed via SPSS Software version 25.0 (IBM Corp).</p></sec><sec sec-type="results"><title>Results</title><p>The study invited 14 key informants, and all were willing to participate in the interview. The completeness and timeliness of reports were 98% and 100%, respectively. The sensitivity, positive predictive value, and representativeness were 45.3%, 92.6%, and 22%, respectively. Nearly three-fourths (10/14, 71%) of key informants perceived the system as flexible, while half thought it as unstable due to factors such as inadequate training and lack of supportive supervision and feedback system. Health facilities did not conduct routine data analysis and interpretation, nor did they use for action.</p></sec><sec sec-type="conclusions"><title>Conclusions</title><p>The surveillance system in Mojo city was simple, flexible, acceptable, and predictive but less sensitive, unrepresentative, and unstable. There is a need for implementing routine data analysis and use for action, adequate training, and feedback system for optimizing the system&#x2019;s performance and to ensure its sustainability.</p></sec></abstract><kwd-group><kwd>hypertension</kwd><kwd>sentinel surveillance</kwd><kwd>public health surveillance</kwd><kwd>noncommunicable disease surveillance</kwd><kwd>Ethiopia</kwd></kwd-group></article-meta></front><body><sec id="s1" sec-type="intro"><title>Introduction</title><p>Hypertension is the leading risk factor for cardiovascular diseases [<xref ref-type="bibr" rid="ref1">1</xref>,<xref ref-type="bibr" rid="ref2">2</xref>]. Approximately 1.28 billion adults aged 30 to 79 years have hypertension worldwide, with low- and middle-income countries bearing two-thirds of the global burden. Alarmingly, 46% of adults with hypertension are unaware of their condition while only 42% received appropriate diagnosis and treatment. Furthermore, 1 in 5 individuals with hypertension have successfully controlled their blood pressure (BP) [<xref ref-type="bibr" rid="ref3">3</xref>]</p><p>While global trends in hypertension have shown significant increases each year, the rise is disproportionately seen in low- and middle-income countries especially in the African region [<xref ref-type="bibr" rid="ref4">4</xref>,<xref ref-type="bibr" rid="ref5">5</xref>]. By the end of 2021, the World Health Organization (WHO) of Africa exhibited the highest prevalence of hypertension (27%) compared with other regions [<xref ref-type="bibr" rid="ref3">3</xref>]. In sub-Saharan Africa, the prevalence has been reported as high as 48% [<xref ref-type="bibr" rid="ref5">5</xref>].</p><p>Hypertension is among one of the rising noncommunicable diseases (NCDs) [<xref ref-type="bibr" rid="ref6">6</xref>-<xref ref-type="bibr" rid="ref8">8</xref>] due to factors such as rapid urbanization, aging population as result of improved life expectancy, globalization of marketing and trade, and exposure to the social determinants of health [<xref ref-type="bibr" rid="ref9">9</xref>,<xref ref-type="bibr" rid="ref10">10</xref>]. The WHO estimated that the prevalence of hypertension in Ethiopia exceeds 20% and is alarmingly increasing over time [<xref ref-type="bibr" rid="ref11">11</xref>]. Data from meta-analyses indicate that the prevalence of hypertension ranges from 9.3% to 30.3% in population-based studies, 7% to 37% in institution-based studies, and 13.2%% to 18.8% in hospital-based studies [<xref ref-type="bibr" rid="ref12">12</xref>]. A substantial gap also exists in hypertension control in the country, with several hospital-based studies reporting BP control rates ranging from 26.4% to 52.5% [<xref ref-type="bibr" rid="ref13">13</xref>-<xref ref-type="bibr" rid="ref16">16</xref>].</p><p>Due to the rising incidence and prevalence of NCDs including hypertension, strengthening of the NCD surveillance system has become increasingly important. The WHO has emphasized the need for improved NCD surveillance systems to effectively tackle NCDs [<xref ref-type="bibr" rid="ref17">17</xref>]. Consequently, Ethiopia has made a significant shift in its approach to public health surveillance. For over 3 decades, the country implemented surveillance of epidemic-prone communicable diseases under public health emergency management system [<xref ref-type="bibr" rid="ref18">18</xref>]. However, country adopted its first NCD-inclusive public health emergency management guideline that included hypertension and diabetes mellitus by 2021 [<xref ref-type="bibr" rid="ref19">19</xref>].</p><p>In addition, to enhance hypertension prevention and control, the Federal Ministry of Health, in collaboration with the WHO and Resolve to Save Lives, initiated a hypertension control project at the primary health care level including 74 health facilities and 200 health posts since 2019 [<xref ref-type="bibr" rid="ref20">20</xref>]. These facilities have been used as hypertension sentinel sites to facilitate early detection, timely response, and data-driven decision making.</p><p>The target population for this surveillance system comprises adults aged 30 years and older. The major milestones of this initiative include screening 30% of the eligible population and achieving a 50% BP control. However, no evaluation has been conducted at either national or subnational levels. Hence, evaluating this program is crucial to ascertain its success and failures, share lessons learnt, guide evidence-based decision making, inform clinical practice, and improve overall hypertension control. Therefore, this study aimed to evaluate on whether the sentinel hypertension surveillance systems in 2 health centers in Mojo City, Oromia region of Ethiopia are operating effectively and efficiently.</p></sec><sec id="s2" sec-type="methods"><title>Methods</title><sec id="s2-1"><title>Study Area</title><p>Mojo City is located in the East Shewa zone, Oromia region of Ethiopia at 74 km distance from Addis Ababa, the capital city of Ethiopia. Based on Ethiopia&#x2019;s 2007 census data, the estimated population of Mojo City was 58,941, of which 51% (30,060) were females. Adults aged 30 years and older constitute 29% (17,093/58,941) of the total population. Mojo City has 1 primary hospital, 2 health centers, and 2 health posts. Mojo City is strategically located along the Ethio-Djibouti railway and was identified by the Ministry as one of the high NCD burden areas in the country.</p></sec><sec id="s2-2"><title>Study Design</title><p>This study used a concurrently embedded a mixed methods approach that combines both quantitative and qualitative data collection strategies at 2 sentinel sites in Mojo City, such as Mojo and Haachaltu Gudina Health Centers, and their 2 administrative institutions, such as the Mojo City health administration office and Oromia regional health Bearau. The evaluation included the performances of these sites from September 1, 2021 to July 30, 2022.</p></sec><sec id="s2-3"><title>Sampling Procedures</title><p>We purposively included the only available 2 sentinel sites in Mojo City, that is, Mojo and Haachaltu Gudina Health Centers. Based on the phenomenon of interest, recommendations from qualitative studies, and practical considerations such as data and resource needs, 14 key informants were purposively selected based on predefined criteria, such as training, experience, education, and position they held.</p><p>We included and reviewed the central triage register of all adults aged 30 years and older, screened for hypertension to identify patients with initially elevated BP. We included all actively followed patients with hypertension for BP control assessment. Also, we randomly took a convenient sample of 20 patients&#x2019; records to assess data completeness and the agreement between cohort register and surveillance reporting platforms. For sensitivity calculation, we compared the proportions of hypertensive cases captured by the surveillance system with those revealed by the survey findings. Finally, we took all individuals having initially raised BP and later confirmed to truly have hypertension to determine positive predictive value (PPV).</p></sec><sec id="s2-4"><title>Data Collection Procedures</title><p>We followed the Centers for Disease Control and Prevention&#x2019;s updated guidelines for evaluating public health surveillance systems to assess the usefulness and 9 attributes of the surveillance system [<xref ref-type="bibr" rid="ref21">21</xref>]. In addition, we adapted the standards for communicable disease surveillance and response systems evaluation to assess the core and supportive surveillance functions such as case detection, investigation and confirmation, communication and reporting, routine data analysis and interpretation, the availability of surveillance platforms, training, and supportive supervision and feedback system [<xref ref-type="bibr" rid="ref22">22</xref>].</p><p>Data were collected using a semistructured questionnaire through face-to-face interviews, observations, and record reviews. Simplicity, flexibility, stability, acceptability, and usefulness were assessed via key informant interviews. A semistructured interview guide was developed in English and translated into the local language, Oromifa. The interview guide was designed in a way that allowed free responses as well as choices from predefined categories, for example, yes or no response-option questions. After the informant consent was obtained from each key informant, the lead author (ADG) conducted 14 face-to-face interviews. Interviews were audio-recorded, notes were taken, and each interview lasted 15 to 30 minutes.</p><p>We assessed data analysis and interpretation practice, availability of surveillance guidelines and standards, supervision and feedback, and timeliness via observations. Using medical record reviews, hypertension screening and case detection, BP control, investigation and confirmation, BMI screening, data quality, PPV, and representativeness were assessed. Both medical record reviews and observations were conducted by trained Bachelor of Science (BSc) degree nurses.</p></sec><sec id="s2-5"><title>Operational Definitions</title><sec id="s2-5-1"><title>Usefulness</title><p>Usefulness refers to the relevance of the surveillance system to detect diseases to injuries, estimate its magnitude, and assess the effects of prevention and control efforts [<xref ref-type="bibr" rid="ref21">21</xref>]. The system was considered &#x201C;useful&#x201D; if it provided accurate and timely data on the magnitude of hypertension in the community, and supported decision-making for health interventions.</p></sec><sec id="s2-5-2"><title>Simplicity</title><p>Simplicity refers to the ease of the surveillance structures and the ease of operation. A &#x201C;simple&#x201D; system was defined as one that required minimal resources, training, time to operate, and avoids complexity about in its information flow.</p></sec><sec id="s2-5-3"><title>Acceptability</title><p>Acceptability refers to the willingness of surveillance personnel and organizations to participate in the surveillance system. The system was considered &#x201C;acceptable&#x201D; if the surveillance staff was willing to implement the system. This was assessed by the status of their active participation in case detection, adherence to case definition, completeness, and timeliness of reporting.</p></sec><sec id="s2-5-4"><title>Timeliness</title><p>Timeliness reflects the speed between steps in a public health surveillance system. Timeliness was calculated by assessing how many of the expected reports have been submitted within the system-prescribed time frame. The system was considered &#x201C;timely&#x201D; if all expected reports have been submitted within a system-defined time frame.</p></sec><sec id="s2-5-5"><title>Data Quality</title><p>Data quality refers to the completeness and validity of the recorded data in the public health surveillance system. It was assessed in terms of data completeness, expressed as the proportion of reports submitted to the next level of health authority, the completeness of surveillance platforms, measured by the proportion of surveillance forms fully recorded, and the validity of the data recorded.</p></sec><sec id="s2-5-6"><title>Flexibility</title><p>Flexibility refers to the ability of the surveillance system to adapt to the changing information needs or operating conditions. A system was considered &#x201C;flexible&#x201D; if it could easily accommodate changing needs, such as addition of new data variables, modification of data collection process, or adjustment of reporting mechanisms.</p></sec><sec id="s2-5-7"><title>Representativeness</title><p>Representativeness refers to the ability of surveillance system to describe the occurrence of health-related events by the person, place, and time characteristics. It was assessed by determining on whether the surveillance system provided an accurate description of hypertension in the target population. The system was considered &#x201C;representative&#x201D; if it included a balanced representation of the surveillance population.</p></sec><sec id="s2-5-8"><title>Stability</title><p>Stability refers to the ability to collect, manage, and provide data properly without failure, and the ability to be operational when needed. The system was considered &#x201C;stable&#x201D; if it operated without significant downtime or data loss during its restructuring or changing needs.</p></sec><sec id="s2-5-9"><title>Sensitivity</title><p>Sensitivity refers to the ability of the surveillance system to accurately identify disease or condition under surveillance. The system was considered &#x201C;sensitive&#x201D; if it could capture hypertensive cases that actually have a disease. This was assessed by comparing the proportion of patients with hypertension captured by the surveillance system and those identified by the baseline survey findings.</p></sec><sec id="s2-5-10"><title>PPV</title><p>PPV refers to the proportion of reported cases that actually have the health-related event under surveillance [<xref ref-type="bibr" rid="ref21">21</xref>]. PPV was assessed by calculating the proportion of surveillance-reported cases that were confirmed as true cases of hypertension. The system was considered &#x201C;positively predictive&#x201D; if could truly identify hypertensive cases.</p></sec></sec><sec id="s2-6"><title>Data Quality Control</title><p>Before the actual data collection, we discussed with key informants to ensure that the evaluation was able to address important questions and gather credible evidence. During each visit of data collection, we briefed participants on the purpose and objective of the evaluation, underscoring that it is not an individual performance evaluation. The entire data collection process was closely monitored by research supervisors and principal investigators.</p></sec><sec id="s2-7"><title>Data Analysis</title><p>The quantitative data were coded, cleaned, and analyzed via SPSS software version 25.0 (IBM Corp) while the qualitative data were analyzed via the following methods. First, we transcribed the audio-recorded data and carefully read the text to obtain a general sense of the content. Second, we identified condensed meaning units and developed initial code books. Code books were designed in a way that they are flexible and devised when novel themes emerged. After the open coding, we created subcategories that merged codes with similar meanings, and subcategories were then combined to establish categories. The data were subsequently analyzed manually, narrated, and summarized via thematic analysis.</p></sec><sec id="s2-8"><title>Ethical Considerations</title><p>The study was approved by the Afar Public Health Institute (approval APH/25/21). We also obtained a collaboration letter from Ethiopia&#x2019;s Ministry of Health, Oromia&#x2019;s Public Health Institute, and Mojo City&#x2019;s Administration Health Office. Before commencement of interview, informed consent was obtained from the participant to ensure their understanding and agreement to the recording process. After each participant understood the purpose, potential risks and benefits of the study, they were orally consented for participation in the study. The participation process was entirely voluntary and no monetary or material compensation was provided to the participants. Such consent and compensation processes were part of the study protocol approved by the ethical approval committee. The data and all collected information were delinked, deidentified, and anonymyzed for confidentiality. They were also kept in a secure file cabinet.</p></sec></sec><sec id="s3" sec-type="results"><title>Results</title><sec id="s3-1"><title>Study Characteristics</title><p>The study invited 14 key informants for interviews, and all were willing to provide an interview. Of these key informants, 4 (29% held master&#x2019;s degrees in public health, 4 (29%) were public health officers, and 6 (42%) were BSc degree nurses, of whom 4 (29%) were surveillance officers, and 2 (14%) were facility heads (<xref ref-type="table" rid="table1">Table 1</xref>).</p><table-wrap id="t1" position="float"><label>Table 1.</label><caption><p>Key informant characteristics. Evaluation of a sentinel hypertension surveillance system in Mojo city, Eastern Shewa, Oromia, Ethiopia, 2022.</p></caption><table id="table1" frame="hsides" rules="groups"><thead><tr><td align="left" valign="bottom">Key informant characteristics</td><td align="left" valign="bottom" colspan="2">Frequency, n (%)</td></tr></thead><tbody><tr><td align="left" valign="top">Title or degree</td><td align="left" valign="top" colspan="2"/></tr><tr><td align="left" valign="top">&#x2003;Master of Public Health</td><td align="left" valign="top" colspan="2">4 (29)</td></tr><tr><td align="left" valign="top">&#x2003;Public Health Officer</td><td align="left" valign="top" colspan="2">4 (29)</td></tr><tr><td align="left" valign="top">&#x2003;Bachelors of Science degree nurses</td><td align="left" valign="top" colspan="2">6 (42)</td></tr><tr><td align="left" valign="top">Location</td><td align="left" valign="top" colspan="2"/></tr><tr><td align="left" valign="top">&#x2003;Mojo Health Center</td><td align="left" valign="top" colspan="2">5 (36)</td></tr><tr><td align="left" valign="top">&#x2003;Haachaltu Gudina Health Center</td><td align="left" valign="top" colspan="2">5 (36)</td></tr><tr><td align="left" valign="top">&#x2003;Mojo City Health Office</td><td align="left" valign="top" colspan="2">2 (14)</td></tr><tr><td align="left" valign="top">&#x2003;Oromia Regional Health Bureau</td><td align="left" valign="top" colspan="2">2 (14)</td></tr><tr><td align="left" valign="top">Work position</td><td align="left" valign="top" colspan="2"/></tr><tr><td align="left" valign="top">&#x2003;Hypertension screening unit</td><td align="left" valign="top" colspan="2">2 (14)</td></tr><tr><td align="left" valign="top">&#x2003;Hypertension focal persons</td><td align="left" valign="top" colspan="2">4 (29)</td></tr><tr><td align="left" valign="top">&#x2003;Surveillance officers</td><td align="left" valign="top" colspan="2">4 (29)</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Data Management</td><td align="left" valign="top" colspan="2">2 (14)</td></tr><tr><td align="left" valign="top">&#x2003;Facility heads</td><td align="left" valign="top" colspan="2">2 (14)</td></tr><tr><td align="left" valign="top">Hypertension training</td><td align="left" valign="top" colspan="2"/></tr><tr><td align="left" valign="top">&#x2003;Trained for hypertension</td><td align="left" valign="top" colspan="2">6 (43)</td></tr><tr><td align="left" valign="top">&#x2003;Untrained for hypertension</td><td align="left" valign="top" colspan="2">8 (57)</td></tr><tr><td align="left" valign="top">Work experience</td><td align="left" valign="top" colspan="2"/></tr><tr><td align="left" valign="top">&#x2003;Junior level (&#x003C;2 y)</td><td align="left" valign="top" colspan="2">2 (14)</td></tr><tr><td align="left" valign="top">&#x2003;Intermediate level (2-&#x003C;5 y)</td><td align="left" valign="top" colspan="2">4 (29)</td></tr><tr><td align="left" valign="top">&#x2003;Senior level (&#x2265;5 y)</td><td align="left" valign="top" colspan="2">8 (57)</td></tr></tbody></table></table-wrap></sec><sec id="s3-2"><title>Description and Operation of the Surveillance System</title><p>The hypertension surveillance system in the Mojo City is a multitiered framework involving various health care providers and administrative personnel. Public health officers and BSc nurses are responsible for identifying and diagnosing hypertension, and initiating antihypertensive treatment. Health information technicians collect and report data, while the administrative staffs oversee data aggregation, analysis, and interpretation and use for action.</p><p>Based on the national clinical guidelines, surveillance system in Mojo City defines hypertension with a systolic blood pressure (SBP) of &#x2265;140 mmHg or a diastolic blood pressure (DBP) of &#x2265;90 mmHg in 2 consecutive visits. BP control is defined as achieving an SBP of &#x003C;140 mmHg and a DBP of &#x003C;90 mmHg in 2 consecutive visits, with the specific targets of &#x003C;130/90 mmHg in patients having comorbidities such as diabetes, chronic kidney disease, and cardiovascular diseases.</p><p>The surveillance system uses both electronic and paper-based reporting platforms to facilitate efficient data flow between health care providers and surveillance officers. The information flow follows a bottom-up approach, with data transmitted from health centers to the city health office and then to the regional health bureau (<xref ref-type="fig" rid="figure1">Figure 1</xref>).</p><fig position="float" id="figure1"><label>Figure 1.</label><caption><p>The information flow and reporting scheme for a sentinel hypertension surveillance system in Mojo city, Eastern Shewa, Oromia, Ethiopia, 2022.</p></caption><graphic alt-version="no" mimetype="image" position="float" xlink:type="simple" xlink:href="ojphi_v17i1e72909_fig01.png"/></fig></sec><sec id="s3-3"><title>Case Detection</title><p>Between September 1, 2021, and July 30, 2022, a total of 3760 adults aged 30 years and older were screened for hypertension. Among those screened, 553 (14.7%) individuals were presented with raised BP, and 512 (13.6%) individuals were confirmed to have hypertension. Of the patients confirmed with hypertension, 76 (14.8%) patients were lost, while 436 (85.2%) were receiving antihypertensive treatment. Only 214 (49%) patients who were on antihypertensive follow-up had achieved controlled BP.</p></sec><sec id="s3-4"><title>Investigation and Confirmation</title><p>A systematic approach was employed to confirm individuals with initially raised BP. Nurses and health officers oversee BP screening and BP confirmation. All patients with raised BP were reassessed for confirmation according to the national clinical guidelines. However, the initiation of antihypertensive therapy lacked essential investigations. Specifically, only 9.7% (50/512) of patients received a baseline renal panel, despite it being a crucial step outlined in the national clinical guidelines and patients may be at higher risk of undiagnosed kidney damage, which could lead to worse outcomes, including kidney failure and cardiovascular complications. The test is essential for evaluating kidney function, detecting early signs of kidney damage, assessing potential comorbidities related to hypertension, such as chronic kidney disease, tailoring treatment plans, and preventing the progression of hypertension-related renal complications. Furthermore, BMI screening, another essential component of hypertension management was not systematically conducted for all patients, with only 25.8% (132/512) of patients with hypertension undergoing this assessment.</p></sec><sec id="s3-5"><title>Communication and Reporting System</title><p>The surveillance system uses Health Management Information System (HMIS) framework of reporting diseases in Ethiopia. Health centers submit reports to Mojo city administration Health Office every 21st-26th of each month. Similarly, Mojo city&#x2019;s administration Health Office subsequently compiled and sent to Oromia Regional Health Bureau within the same time frame. The Oromia Regional Health Bureau further transmits reports to the Federal Ministry of Health within the same reporting schedule. This type of surveillance system was fully implemented throughout the year and maintained through both electronic and paper-based reporting system (<xref ref-type="fig" rid="figure1">Figure 1</xref>).</p></sec><sec id="s3-6"><title>Data Analysis, Interpretation, Action, and Response</title><p>Health facilities did not conduct routine data analysis, resulting in hypertension data that lacked specific information regarding time, place, and person characteristics. In addition, there were no established action thresholds for the interpretation of data or for formulating appropriate responses.</p></sec><sec id="s3-7"><title>Availability of Surveillance Guidelines, Standards, and Other Resources</title><p>The surveillance system in the Mojo City ensured the continuous supply of essential surveillance forms, standards, and guidelines. Both health facilities had sufficient back up store of tally sheets, intake forms, follow-up forms, referral forms, and cohort registers. However, health facilities had the shortage of appointment forms and tablets for SIMPLE App (Resolve To Save Lives), a smart app designed for tracking patient follow-up.</p></sec><sec id="s3-8"><title>Supervision, Feedback, and Training</title><p>Neither Ethiopia&#x2019;s Federal Ministry of Health nor the Oromia Regional Health Bureau provided written feedback regarding the performance of health facilities. Only 6 out of 14 (43%) of key informants received hypertension training. In addition, the heads of health facilities expressed concerns about inadequate training and backup staff to manage staff turnover and annual leave.</p></sec><sec id="s3-9"><title>Usefulness and Surveillance System Attributes</title><sec id="s3-9-1"><title>Usefulness</title><p>All 14 key informants (100%) indicated that the surveillance system was valuable, as its record-keeping capabilities documented data that highlighted the magnitude of hypertension in the area and helped them to integrate hypertension service at the community-level involving community health extension workers. One participant noted:</p><disp-quote><p>I found the existing system immensely important because it helped us understand the extent of the hypertension problem in the area, evaluate our efforts in prevention and control, and improve chart keeping. I believe the lessons learned will be instrumental for further program expansion. [Participant 5, Head of Health Care Site X]</p></disp-quote></sec><sec id="s3-9-2"><title>Acceptability</title><p>The active participation of surveillance staff in case detection, adherence to case definitions, and report completeness and timeliness demonstrated their full commitment to implementing the surveillance system. One participant expressed:</p><disp-quote><p>I am very happy being the hypertension focal person at the health facility and part of this sentinel surveillance system. I am fully committed to hypertension screening and case detection, utilizing case definitions, and providing timely and complete surveillance reports. [Participant 6, Hypertension Focal Person from Facility Y]</p></disp-quote></sec><sec id="s3-9-3"><title>Simplicity</title><p>All 14 (100%) of key informants agreed that the current case definition was clear, easy to understand, and apply, and that reporting platforms are user-friendly, requiring average completion time of 10&#x2010;15 minutes. They noted that the route of information flow was clear and well-delineated. They also reported that the SIMPLE App is intuitive and required minimal or no training for data entry and updates. One participant stated:</p><disp-quote><p>... Without any reservation, in my view, the hypertension case definition is easy for me to understand and apply, and I am able to complete surveillance forms within a matter of 10 minutes. I am also clear with for whom to report, reporting period, and formats used for reporting. [Participant 9, surveillance officer from health care site Y]</p></disp-quote></sec><sec id="s3-9-4"><title>Flexibility</title><p>In total, 10 out of 14 key informants (71%) thought that the current reporting form could be easily adapted to new health events, and that case definition of hypertension was flexible enough to accommodate changes. The system has previously experienced significant changes in case definition and its treatment targets, and that they did not face much difficulty in both aspects. This adjustment shifted the focus from individuals aged 18 years and older to those aged 30 years and older for BP screening, as well as updated BP control treatment targets of BP below 130/90 mmHg for patients with hypertension having diabetes, chronic kidney disease, and cardiovascular conditions. One participant stated:</p><disp-quote><p>I think we can modify the current case definition slightly to allow for other events. Moreover, I believe the current system can operate with varying funding sources, as it was once well established. [Participant 3, Nurse at the Hypertension Screening Unit from Health Care Site X]</p></disp-quote></sec><sec id="s3-9-5"><title>Stability</title><p>Out of 14, 7 participants (50%) of the surveillance staff noted that restructuring during the down times of the computer system breakage did not affect the operation of surveillance system and that surveillance system was able to continue to collect, manage, and provide data properly without failure. However, the other half-expressed concerns regarding the adequacy of trained backup staff and the program&#x2019;s dependency on a partner, citing insufficient input from local and regional governments. One participant noted:</p><disp-quote><p>There is a common practice in Ethiopia: programs supported by partners and external sources tend to be more effective, but the challenge arises when they are left to operate independently. Our system is similarly dependent on the partner; how could it continue if the partner withdraws support? I have serious concerns about its sustainability. [Participant 2, Surveillance Officer from Administrative Institution B]</p></disp-quote></sec><sec id="s3-9-6"><title>Timeliness</title><p>For all 11 months included in the evaluation, reports between each reporting units in the surveillance chain, specifically from health facilities to the Mojo City Administration Health Office, from the Mojo City Administration Health Office to the Oromia Regional Health Bureau, and from the Oromia Regional Health Bureau to the Federal Ministry of Health were submitted according to HMIS framework for reporting diseases in Ethiopia between the 21st and 26th of each month (<xref ref-type="fig" rid="figure2">Figure 2</xref>).</p><fig position="float" id="figure2"><label>Figure 2.</label><caption><p>The report timeliness and completeness in a hypertension sentinel surveillance system in Mojo City, East Shewa Zone, Oromia region, Ethiopia, 2022.</p></caption><graphic alt-version="no" mimetype="image" position="float" xlink:type="simple" xlink:href="ojphi_v17i1e72909_fig02.png"/></fig></sec><sec id="s3-9-7"><title>Data Quality</title><p>Of the 20 patient medical records reviewed, 17 (85%) patient charts and follow-up forms were complete, neat, and filled in an easily understandable manner. The agreement between patient charts and cohort register was observed for all these patients. The completeness of the reports over the 11 months of review was 98% (<xref ref-type="fig" rid="figure2">Figure 2</xref>).</p></sec><sec id="s3-9-8"><title>Representativeness</title><p>By screening 3760 adults aged 30 years and older from a corresponding target population of 17,000 inhabitants, the surveillance system reached 22% of the target population. The system identified 512 patients with hypertension, of whom 352 (69%) were reported from the Mojo Health Center, and 270 (52.9%) were females.</p></sec><sec id="s3-9-9"><title>PPV and Sensitivity</title><p>The BP screening and confirmation practices were taken to calculate PPV. Of the 553 patients with initially raised BP levels, that is, SBP &#x2265;140 mmHg or DBP &#x2265;90 mmHg, 512 (92.6%) individuals truly had hypertension after reassessment (PPV). Similarly, to assess sensitivity, we used a 30% prevalence of hypertension from a baseline facility-based survey conducted in 2020 using a representative sample as a benchmark and compared the current proportion of patients with hypertension identified by the surveillance system (512/3760, 13.6%). Thus, the sensitivity of the surveillance system was 45.3% (<xref ref-type="table" rid="table2">Table 2</xref>).</p><table-wrap id="t2" position="float"><label>Table 2.</label><caption><p>A performance comparison table showing system attributes in a hypertension surveillance system in Mojo City, East Shewa Zone, Oromia region, Ethiopia, 2022.</p></caption><table id="table2" frame="hsides" rules="groups"><thead><tr><td align="left" valign="bottom">System attributes</td><td align="left" valign="bottom">Haachaltu Gudina health center</td><td align="left" valign="bottom">Mojo health center</td><td align="left" valign="bottom">Mojo city health office</td><td align="left" valign="bottom">Conclusion</td></tr></thead><tbody><tr><td align="left" valign="top">Usefulness</td><td align="left" valign="top">Useful</td><td align="left" valign="top">Useful</td><td align="left" valign="top">Useful</td><td align="left" valign="top">Useful</td></tr><tr><td align="left" valign="top">Acceptability</td><td align="left" valign="top">Acceptable</td><td align="left" valign="top">Acceptable</td><td align="left" valign="top">Acceptable</td><td align="left" valign="top">Acceptable</td></tr><tr><td align="left" valign="top">Simplicity</td><td align="left" valign="top">Simple</td><td align="left" valign="top">Simple</td><td align="left" valign="top">Simple</td><td align="left" valign="top">Simple</td></tr><tr><td align="left" valign="top">Flexibility</td><td align="left" valign="top">Flexible</td><td align="left" valign="top">Flexible</td><td align="left" valign="top">Flexible</td><td align="left" valign="top">Flexible</td></tr><tr><td align="left" valign="top">Stability</td><td align="left" valign="top">Unstable</td><td align="left" valign="top">Unstable</td><td align="left" valign="top">Unstable</td><td align="left" valign="top">Unstable</td></tr><tr><td align="left" valign="top">Representativeness</td><td align="left" valign="top">(1650/7534, 21.9%)</td><td align="left" valign="top">(2110/9466, 22.3%)</td><td align="left" valign="top">(3760/17,000, 22%)</td><td align="left" valign="top">Unrepresentative</td></tr><tr><td align="left" valign="top">Data completeness</td><td align="left" valign="top">(505/520, 97.1%)</td><td align="left" valign="top">(552/559, 98.7%)</td><td align="left" valign="top">(1057/1079, 98%)</td><td align="left" valign="top">High</td></tr><tr><td align="left" valign="top">Timeliness</td><td align="left" valign="top">(11/11, 100%)</td><td align="left" valign="top">(11/11,100%)</td><td align="left" valign="top">(11/11,100%)</td><td align="left" valign="top">High</td></tr><tr><td align="left" valign="top">Sensitivity</td><td align="left" valign="top">43.5%</td><td align="left" valign="top">47.1%</td><td align="left" valign="top">45.3%</td><td align="left" valign="top">Low</td></tr><tr><td align="left" valign="top">Positive predictive value</td><td align="left" valign="top">91.8%</td><td align="left" valign="top">93.4%</td><td align="left" valign="top">92.6%</td><td align="left" valign="top">High</td></tr></tbody></table></table-wrap></sec></sec></sec><sec id="s4" sec-type="discussion"><title>Discussion</title><sec id="s4-1"><title>Principal Findings</title><p>We followed the Centers for Disease Control and Prevention&#x2019;s updated guidelines for evaluating public health surveillance systems to assess on whether the existing surveillance system in Mojo City operated effectively and efficiently. The usefulness and 9 system attributes were streamlined in this evaluation. Accordingly, the surveillance system in Mojo city was useful, simple to operate, flexible to changing needs, acceptable by surveillance staff, has higher PPV but less sensitive, unrepresentative, and unstable.</p><p>While the surveillance system in Mojo City was fully operational throughout the year, it lacked regular supportive supervision and feedback mechanisms. There is need to institutionalize periodic evaluations, enhance the system&#x2019;s functionality, and foster a continuous improvement. Public health surveillance system should be periodically evaluated to provide scientifically sound and epidemiologically interpreted feedbacks for performance and further for its improvement [<xref ref-type="bibr" rid="ref22">22</xref>,<xref ref-type="bibr" rid="ref23">23</xref>].</p><p>All surveillance staff expressed willingness to implement the system and noted that it was both useful and simple. Half perceived the surveillance system stable, while 71% (10/14) thought that it was flexible. Similarly, the performance of public health surveillance system in Dangila, Ethiopia, was found flexible and useful [<xref ref-type="bibr" rid="ref24">24</xref>]. Furthermore, a hypertension surveillance system evaluation conducted in Indonesia at 2 health centers and 1 administrative office reported an overall low stability, simplicity, acceptability, and data quality, but the researchers were unable to assess flexibility [<xref ref-type="bibr" rid="ref25">25</xref>]. However, unlike this study, researchers relied on data collection, storage, and reporting to assess stability, rather than using key informant interviews [<xref ref-type="bibr" rid="ref25">25</xref>].</p><p>Given that 3760 adults aged &#x2265;30 years were screened for hypertension out of a corresponding population of 17,000 inhabitants, the surveillance system in a Mojo City demonstrated low representativeness, having reached only 22% of the population. However, in a hypertension surveillance evaluation conducted in Indonesia, they were unable to assess representativeness of surveillance system [<xref ref-type="bibr" rid="ref25">25</xref>]. The low representativeness in the present surveillance system may be attributed to low community awareness and routine BP screening, and regular medical checkup tradition, which could leave significant numbers of undiagnosed patients in the community. In this system, health centers collect data and report it to the Mojo City Health Office and the Oromia Regional Health Bureau. However, health facilities did not conduct routine data analysis or interpretation, nor did they use the information to inform action. Data collection necessitates analysis because the goal of surveillance is to use the information for action, reduce morbidity and mortality, and to improve overall health [<xref ref-type="bibr" rid="ref22">22</xref>,<xref ref-type="bibr" rid="ref23">23</xref>]. If the collected data are not followed by regular analysis and the application of information for action, it results in the mere consumption of resources [<xref ref-type="bibr" rid="ref26">26</xref>].</p><p>Public health surveillance systems should operate in a manner that facilitates effective communication and dissemination of health and health-related data, enabling decision-makers at all levels to readily understand the implications of the information. Timeliness of reporting is a crucial factor for the effective communication and dissemination of health and health-related data. The report timeliness in the current surveillance system was 100%, which aligns with the Ethiopian national target of 95% [<xref ref-type="bibr" rid="ref27">27</xref>] and the WHO target of 80% [<xref ref-type="bibr" rid="ref28">28</xref>]. In addition, data completeness was 98%, consistent with the national target of over 95% for report completeness [<xref ref-type="bibr" rid="ref27">27</xref>] and the WHO target of 80% [<xref ref-type="bibr" rid="ref28">28</xref>].</p><p>The sensitivity and PPV of a surveillance system depend on the design of the case definition and its clarity among stakeholders [<xref ref-type="bibr" rid="ref29">29</xref>]. The surveillance system in Mojo City exhibited a sensitivity of 45.3%, capturing only 45.3% of hypertension cases and more than half (54.7%) of the individuals with hypertension may be missed by the system. It is less sensitive than the hypertension surveillance system in Bogor City, Indonesia, which has a sensitivity of over 80% [<xref ref-type="bibr" rid="ref30">30</xref>]. The low sensitivity may be attributed to low health care service utilization and suboptimal BP screening practice, as only 22% of the surveillance population was screened for BP. In a hypertension surveillance system evaluation at the Jombang District Health Office, Indonesia, they were unable to calculate sensitivity due to the lack of baseline survey data for comparison. However, the PPV of our surveillance system was 92.6%, indicating that the system correctly identifies 92.6% of true cases of hypertension. It is more predictive when compared with other hypertension surveillance systems in Dangila, Ethiopia which has PPV of 11% [<xref ref-type="bibr" rid="ref24">24</xref>] and Jombang District Health Office of the other city in Indonesia which has PPV of 59.4% [<xref ref-type="bibr" rid="ref25">25</xref>].</p></sec><sec id="s4-2"><title>Limitations of the Study</title><p>The limitations of this evaluation are as follows. First, the results may have been subject to potential social desirability bias, as surveillance stakeholders may have provided favorable responses especially qualitative attributes such as acceptability and simplicity. The surveillance stakeholders may have been inclined to provide more favorable responses to questions about these attributes, potentially overestimating the true level of satisfaction or ease with the surveillance system. To mitigate this, we briefed them on the purpose and objectives of the evaluation at each visit before commencing data collection. Second, reliance on a convenience sample of 20 patients may not have provided a representative assessment of data validity. Third, although this evaluation followed the Centers for Disease Control and Prevention&#x2019;s updated guidelines for evaluating public health surveillance systems as applied in previous studies conducted in different settings to gather credible evidence on the performance of the surveillance system, it is primarily relied on responses from key informant interviews rather than objective quantitative data collection, storage, and reporting, unlike other studies. Finally, the availability of the limited data in the field led to insufficient understanding of surveillance systems in similar contexts and a few of interpretations were made compared with surveillance systems in other country which may have structural and contextual difference with our surveillance system.</p></sec><sec id="s4-3"><title>Conclusion</title><p>The sentinel hypertension surveillance system in Mojo demonstrated effective implementation throughout the year. The surveillance staff felt that it was helpful in determining the magnitude of hypertension in the area as well as for improving documentation and patient record keeping practices. It was found to be simple, flexible, acceptable, and have a higher PPV. The data quality and reporting timeliness were consistent with national and WHO surveillance standards. However, it was less sensitive, less representative, and unstable.</p><p>The findings underscore the need for institutionalization of periodic evaluations and supportive supervision mechanisms to assess the system&#x2019;s performance, provide feedback, and identify areas for improvement. The system should implement routine data analysis and interpretation mechanisms based on epidemiological principles to interpret the collected data, identify trends, and target tailored public health interventions. Continuous staff training on data collection, surveillance protocols, and the operation of the surveillance system should be designed to enhance stability. Furthermore, designing of government-driven sustainability strategies, such as establishment of dedicated public health financing system and consistent resource allocation and capacity building, and cross-sectoral collaborations with local governments, could reduce reliance on external donors and enhance the sustainability of the surveillance system. Efforts should also focus on community awareness creation activities to improve sensitivity and representativeness of the surveillance system. Finally, if resources permit, scaling the system into a nationwide program could significantly enhance hypertension surveillance across Ethiopia.</p></sec></sec></body><back><ack><p>The authors would like to thank Ethiopian Field Epidemiology Training Program, Oromia Public Health Institute, Mojo City Administration Health Office, Mojo and Haachaltu Gudina health centers, health workers, and data collectors.</p><p>All authors declared that they had insufficient funding to support open access publication of this manuscript, including from affiliated organizations or institutions, funding agencies, or other organizations. JMIR Publications provided article processing fee support for the publication of this article.</p></ack><fn-group><fn fn-type="con"><p>ADG conceived the research idea, designed and conducted the study, acquisition of data, analyzed the data, and drafted the article. DZW provided substantial contributions to the design of the study and drafted the article. YAF conducted an extensive manuscript review and structuring. AYE provided substantial contributions to conception and design, or analysis and interpretation of data; and drafting the article or revising it critically for important intellectual content. All the authors have read and approved the final manuscript contributed to conception and design.</p></fn><fn fn-type="conflict"><p>None declared.</p></fn></fn-group><glossary><title>Abbreviations</title><def-list><def-item><term id="abb1">BP</term><def><p>blood pressure</p></def></def-item><def-item><term id="abb2">BSc</term><def><p>Bachelors of Science</p></def></def-item><def-item><term id="abb3">DBP</term><def><p>diastolic blood pressure</p></def></def-item><def-item><term id="abb4">HMIS</term><def><p>Health Management Information System</p></def></def-item><def-item><term id="abb5">NCD</term><def><p>noncommunicable disease</p></def></def-item><def-item><term id="abb6">PPV</term><def><p>positive predictive value</p></def></def-item><def-item><term id="abb7">SBP</term><def><p>systolic blood pressure</p></def></def-item><def-item><term id="abb8">WHO</term><def><p>World Health Organization</p></def></def-item></def-list></glossary><ref-list><title>References</title><ref 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