Arizona is facing multiple threats from mosquito-borne diseases. Traditional surveillance, however, may take as long as 14 days between specimen collection and laboratory reporting to the health department. The Arizona Department of Health Services partnered with local public health jurisdictions to enhance traditional arboviral surveillance by incorporating syndromic surveillance. The objectives of this project were to develop a protocol for enhancing traditional arboviral surveillance with syndromic surveillance and to evaluate the protocol for accuracy, effectiveness, and timeliness.