Armed conflict and the crisis in Ukraine led to the destruction of health care facilities. The refugees dispersed throughout Ukraine, including in the Kharkiv region, bordering the Lugansk and Donetsk regions. There was a threat of importation and spread of communicable diseases. The measles situation has been worsened. To achieve the goals of eliminating measles in spite of the crisis in Ukraine implementation of the syndromic surveillance of measles should be continued in order to identify all the cases fully.