Public health surveillance is essential for early detection and rapid response to cholera outbreaks. In 2003, Cameroon adopted the integrated disease surveillance and response (IDSR) strategy. We describe cholera surveillance within IDSR-strategy in Cameroon. Data is captured at health facility, forwarded to health district that compiles and directs data to RDPH in paper format. RDPH sends the data to the national level via internet and from there to the WHO. The surveillance system is passive with no data analysis at districts. Thus the goal of IDSR-strategy of data analysis and rapid response at the district has not been met yet.