The goal of this analysis is to compare the results of influenza-like-illness (ILI) text and International Classification of Diseases (ICD) code classifiers applied to the Louisiana Office of Public Health (OPH) syndromic surveillance data reported by New Orleans area emergency departments and the Greater New Orleans Health Information Exchange (GNOHIE) data reported by New Orleans area outpatient clinics. This study adds to the evidence supporting the emerging use of outpatient data for syndromic surveillance.