BioSense 2.0 protects the health of the American people by providing timely insight into the health of communities, regions, and the nation by offering a variety of features to improve data collection, standardization, storage, analysis, and collaboration. This presentation will highlight the architecture of the BioSense 2.0 system, covering the interfaces that data providers use to send data to BioSense and the many methods of viewing the critical public health data contained in the BioSense 2.0 system.