This poster presents findings from the National HIV Behavioral Surveillance (NHBS) in New Orleans. These data outline relevant high-risk behaviors among Injection Drug Users (IDU). Risk behaviors and demographic profiles are contrasted for three consecutive representative samples over time. These data can aid in tailoring activities to meet the needs of IDU in New Orleans engaging in high-risk behaviors. Furthermore, these results may inform and direct prevention programs in order to better structure outreach and educational materials.