This presentation will detail the technical hurdles with reading a meaningful use syndromic surveillance data feed containing multiple sources, deriving a common meaning from the varying uses of the standard and writing data out to a meaningful use HL7 2.5 format that can be exported to other tools, such as BioSense 2.0. The presentation will also describe the technologies employed for facilitating this, such as Mirth, and will discuss how other systems could utilize these tools to also support processing meaningful use syndromic surveillance data.