Existing synergies between human and animal health syndromic surveillance (SyS) in Europe and proposal to enhance this collaboration are presented based on the outputs of the European Triple-S project. For the time being, collaborations are limited to regular meetings to discuss outputs of the human and animal health systems. Two reasons for enhancing synergies were highlighted. First, experts on both sides face common statistical and epidemiological issues when dealing with SyS and could thus share their experiences. Second, animal and human SyS systems can target similar health threats. Triple-S guidelines for implementation of SyS systems will aim at promoting synergy.